Sunday, February 27, 2005

Study and blog at the same time

Zyban (buproprion)

Unknown mode of action. Presumably neurochemical.

Used in nicotine withdrawal in assoc w counselling

Contraindications
allergic
seizures
MAOI use (has a slight antidepressant property)

Adverse effects
insomnia, nightmares, dizziness, agitation, anxiety, fever, rash, itch, nausea, constipation etc
palpitations
can predispose to seizures

Come back if: you develop a rash, lips swelling, breathing probs
Don't drink alcohol much (seizures)
Can cause drowsiness (machinery/driving)

Dosage
Start at least 7 days before smoking cessation
150mg mane initially for 3 days, then 150 mg bd for 7-9 weeks
(Take in morning to avoid sleep disturbances)
Assess in 7 weeks. Discontinue if marked reduction in smoking has not been achieved.

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